Simple and cost effective spectrophotometric methods were developed for the determination of almotriptan. Colorometric methods were developed with the reagents MBTH , tropaeolin ooo , Brucine , Alizarin red.S , 2,4 bi pyrimidine, 1,10 Phenanthroline FC, K3FECN6 ,PNA ,and woolfat blue .All the proposed methods obeyed Beer’s Law was . The experimental parameters were optimized and validated. The statistical analysis of results revealed high accuracy and good precision. The proposed methods were successfully applied for the determination of almotriptan active pharmaceutical ingredient (API) in bulk drug.
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